viral
DNA used for replication AND transcription.
virus
Adenovirus bronchiolitis, ear infection.
animal_virus
VIRUS LOTTERY. Flu=RNA Orthomyxovirus
HIV
Note glycoproteins. Lyses T cells but not initial macrophages; killed by cytotoxic T.
HIV life cycle: reverse transcriptase, integrase, protease
HIV treatment: AZT blocks reverse transcriptase
HIV treatment: Ritonavir protease inhibitor
Endogenous retroviruses: life cycle and ancestral implications
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19&E:
RNA-binding regulatory protein - NOT
lac repressor that binds to operator (DNA);
binds to 5? untranslated region (5? UTR) of mRNA, preventing ribosome attachment (UNUSED).
1=C 2=A 3=A? 4=A 5=E identical
6=A? 7=C 8=C 9=B 10=B? ... division
- euchromatin: extended form
- heterochromatin: highly packed
- Amino end of protein: other end is carboxyl
- Histone acetylation: acetyl groups (—COCH3) attached to positively charged lysines, neutralizes positive histone tails,
no longer bind to neighboring nucleosomes.
Histone methylation leads to chromatin condensation.
DNA methylation (esp. Cytosine): repress transcription.
- Control elements: proximal close to promoter, distal far or in intron.